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Results Data were examined for 5 821 757 inpatients (mean age, 56.4 years 51.5% women), including 125 807 in-hospital deaths.

Incidence rate ratios (IRRs) for hospital admissions and hospital mortality counts, as well as relative mortality risks (RMRs) comparing 2016-2019 with 2020 (exposure to the SARS-CoV-2 pandemic), were calculated with Poisson regression with log-link function. Disease groups were defined according to International Statistical Classification of Diseases and Related Health Problems, 10th Revision ( ICD-10 German modification) encoded main discharge diagnoses. Main Outcomes and Measures Administrative data were analyzed from January 1, 2016, to March 31, 2021, as a consecutive sample for all inpatients. Objective To investigate hospitalization rates and compare in-hospital mortality rates with absolute mortality incidences across a broad spectrum of diseases, comparing 2020 data with those of prepandemic years.ĭesign, Setting, and Participants Retrospective, cross-sectional, multicentric analysis of administrative data from 5 821 757 inpatients admitted from January 1, 2016, to December 31, 2020, to 87 German Helios primary to tertiary care hospitals. Reports about excess mortality in this regard have mostly focused on overall death counts during specific pandemic phases. Importance Throughout the ongoing SARS-CoV-2 pandemic, it has been critical to understand not only the viral disease itself but also its implications for the overall health care system. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.